Omphalocele with Fetal Distress

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Journal of Women’s Health and Reproductive Medicine delivers the advancements diagnostic procedures, therapeutic protocols for the management of diseases, and innovative research in gender-based biology that impacts patient care and treatment. It publishes researches & reviews articles that are related to women’s health and their health issues.

One of the anterior abdominal wall defects is an Omphalocele and it is thought to result from an abnormality of folding during development. The incidence of Omphalocele is 1 in 4000 to 5000 live births. It is characterized by a defect at the umbilicus through which bowel and other Intra-abdominal viscera herniate and are covered by a thin membrane consisting of the amnion, Wharton’s jelly, and peritoneum. The cause of Omphalocele is not yet known; there are theories that have been put forward, such as the failure of the bowel to return into the abdomen by 10-12 weeks, failure of the central migration of lateral mesodermal folds, and persistence of the body stalk beyond 12 weeks of gestation. Other fetal and congenital anomalies may also be associated with Omphalocele. Chromosomal abnormalities are seen in greater than 70% of cases. Omphalocele during the antenatal period may be detected either during the routine ultrasonographic examination or while investigating the cause of an increased alpha-fetoprotein. The index case was discovered incidentally during routine obstetrics scan and the case report is therefore aimed at re-echoing the utilities of this modality in its management.

Fetal Omphalocele is the commonest fetal anterior abdominal wall defect. With the widespread use of ultrasound in the antenatal period, it is possible to diagnose this condition now. Follow up of this condition during the prenatal period is necessary. The appropriate decision as to the mode of delivery should be at term, taken in the absence of any emergency.

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Regards,
Robert John
Editorial Manager
Journal of Womens Health and Reproductive Medicine