Peritoneal dialysis (PD) is a commonly used form of renal replacement therapy for patients that have reached end-stage renal disease. Acute bacterial peritonitis (ABP) in chronic PD patients results in pain, increased costs, injury to the peritoneal membrane, and PD modality failure. Optimal antibiotic treatment of acute bacterial peritonitis (ABP) in chronic PD patients should be intraperitoneal, outpatient-based, appropriate, prompt, and uninterrupted. We investigated the frequency of and predisposition to suboptimal antibiotic courses for ABP in our chronic PD patients.Peritoneal dialysis (PD) is an effective home-based renal replacement modality for patients with end stage kidney disease. The peritoneal lining functions as the semipermeable membrane for dialysis, once PD fluid is instilled into the peritoneal space via an indwelling catheter.

PD is the dialysis modality for approximately 11% of the global dialysis population. Acute bacterial peritonitis (ABP) is a common complication of PD, usually presenting with cloudy PD effluent and abdominal pain. Although ABP episodes rarely result in death, severe or prolonged infection may cause peritoneal membrane failure and in fact is the main reason for change in dialysis modality from PD to in-center hemodialysis.Best practice guidelines recommend intraperitoneal as the preferred route of antibiotics for the treatment of ABP. Unless features of sepsis or intractable pain are present, ABP should be treated on an outpatient basis. Once a sample of dialysis effluent has been collected in the peritoneal dialysis clinic (PDC) or the emergency room (ER) and sent for analysis, intraperitoneal antibiotics should be administered without delay, with daily antibiotic therapy to continue for 14 – 21 days, depending upon the organism cultured.

visit for more articles at  Journal of Clinical & Experimental Nephrology

Kindly submit your article at https://www.imedpub.com/submissions/clinical-experimental-nephrology.html or nephrology@eclinicalsci.com 

Regards
Mishita
Jornal co-ordinator
Journal of Clinical & Experimental Nephrology